TMEM107

Across TCGA cell cohorts, TMEM107 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,625 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM107-associated GO terms across cancer lineages are Telomere assembly, Eosinophil activation, and Eosinophil degranulation. Each is linked with TMEM107 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM107-to-partner and partner-to-TMEM107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by TMEM107-low versus TMEM107-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM107→partner) and Y-score (partner→TMEM107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Telomere assembly →	+0.148	+1.517	<.001	<.001	3	11
URINARY_TRACT	Eosinophil activation →	+0.199	+1.023	<.001	.005	2	12
URINARY_TRACT	Eosinophil degranulation →	+0.199	+1.023	<.001	.005	2	12
URINARY_TRACT	Eosinophil activation involved in immune response →	+0.199	+1.023	<.001	.005	2	12
URINARY_TRACT	Regulation of establishment of protein localization to chromosome →	+0.104	+1.055	<.001	.003	3	10
OVARY	D-amino acid metabolic process →	+1.037	+0.779	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,625 associations by consensus.

Telomere assembly by TMEM107 expression — BREAST

Explore this box plot interactively →