TMEM104

Across TCGA patient cohorts, TMEM104 protein abundance is significantly associated with the RNA expression of many other genes, with 8,370 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM104-associated genes across cancer lineages are ARID3A, CMTM3, and RNU1-134P. Each is linked with TMEM104 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM104-to-partner and partner-to-TMEM104 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM104 versus ARID3A in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM104→partner) and Y-score (partner→TMEM104) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ARID3A →	+0.587	+0.539	.007	.006	3	2
OV	CMTM3 →	+0.728	+0.475	.002	.001	3	2
BRCA	RNU1-134P →	-0.816	-0.333	<.001	.007	3	2
BRCA	RNASEH1-AS1 →	-0.876	-0.333	.001	.007	3	2
OV	BDH2 →	+0.720	+0.553	<.001	<.001	3	2
BRCA	MIR6088 →	+2.260	+0.333	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,370 associations by consensus.

TMEM104 vs ARID3A — HNSC

Explore this scatter interactively →