TMEFF1

Across TCGA patient cohorts, TMEFF1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,539 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEFF1-associated genes across cancer lineages are SEZ6L, SEPTIN3, and CYP2D6. Each is linked with TMEFF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEFF1-to-partner and partner-to-TMEFF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEFF1 versus SEZ6L in GBM, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEFF1→partner) and Y-score (partner→TMEFF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEZ6L →	+2.670	+1.304	.005	.003	3	1
GBM	SEPTIN3 →	+2.634	+1.313	<.001	.001	3	1
GBM	CYP2D6 →	+1.331	+1.271	.002	.007	3	1
GBM	XBP1 →	-0.765	-1.141	<.001	.003	3	1
GBM	SBF1 →	+0.821	+1.123	.004	.008	3	1
GBM	NEFH →	+1.641	+1.223	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,539 associations by consensus.

TMEFF1 vs SEZ6L — GBM

Explore this scatter interactively →