TMEFF1

Across TCGA patient cohorts, TMEFF1 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,570 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEFF1-associated proteins across cancer lineages are RBMS1, TMEFF2, and TMEM178B. Each is linked with TMEFF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEFF1-to-partner and partner-to-TMEFF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEFF1 versus RBMS1 in GBM, with a Pearson correlation of -0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEFF1→partner) and Y-score (partner→TMEFF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBMS1 →	-0.671	-1.058	<.001	<.001	3	1
GBM	TMEFF2 →	+1.798	+1.177	<.001	<.001	3	1
GBM	TMEM178B →	+0.813	+0.991	<.001	.003	3	1
GBM	TMEM214 →	-0.567	-1.207	<.001	.002	3	1
GBM	TMEM43 →	-0.677	-1.276	<.001	<.001	3	1
GBM	TMEM74B_S222 →	+1.062	+1.334	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,570 associations by consensus.

TMEFF1 vs RBMS1 — GBM

Explore this scatter interactively →