TMEFF1

Across TCGA cell cohorts, TMEFF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,871 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEFF1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Protein-DNA complex assembly, and Protein-DNA complex organization. Each is linked with TMEFF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both TMEFF1-to-partner and partner-to-TMEFF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by TMEFF1-low versus TMEFF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEFF1→partner) and Y-score (partner→TMEFF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.096	+1.701	<.001	<.001	3	17
BONE	Protein-DNA complex assembly →	+0.074	+1.314	<.001	<.001	3	16
BONE	Protein-DNA complex organization →	+0.081	+1.314	<.001	<.001	3	16
STOMACH	RNA export from nucleus →	+0.113	+0.848	<.001	.006	3	16
BONE	Epigenetic regulation of gene expression →	+0.096	+1.835	<.001	<.001	3	16
BONE	Cell cycle G1/S phase transition →	+0.095	+1.466	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,871 associations by consensus.

DNA-templated transcription initiation by TMEFF1 expression — BONE

Explore this box plot interactively →