TMED10

Across TCGA cell cohorts, TMED10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,952 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMED10-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and Endoplasmic reticulum to cytosol transport. Each is linked with TMED10 in more than 18 cancer types. Because this analysis shows association rather than direction, both TMED10-to-partner and partner-to-TMED10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by TMED10-low versus TMED10-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMED10→partner) and Y-score (partner→TMED10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.183	+0.896	<.001	<.001	3	19
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.183	+0.896	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Endoplasmic reticulum to cytosol transport →	+0.152	+0.849	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Retrograde protein transport, ER to cytosol →	+0.152	+0.849	<.001	<.001	3	15
BONE	Protein exit from endoplasmic reticulum →	+0.149	+0.929	<.001	.002	3	15
LUNG_NSCLC_LUSC	Post-translational protein targeting to membrane, translocation →	+0.108	+0.716	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,952 associations by consensus.

Protein catabolic process at synapse by TMED10 expression — BLOOD_Lymphoma

Explore this box plot interactively →