TMCO5A

Across TCGA cell cohorts, TMCO5A RNA expression is significantly associated with the go_rna of many other GO terms, with 455 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TMCO5A-associated GO terms across cancer lineages are Apoptotic cell clearance, Tie signaling pathway, and Blood coagulation, intrinsic pathway. Each is linked with TMCO5A in more than 3 cancer types. Because this analysis shows association rather than direction, both TMCO5A-to-partner and partner-to-TMCO5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic cell clearance grouped by TMCO5A-low versus TMCO5A-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO5A→partner) and Y-score (partner→TMCO5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Apoptotic cell clearance →	+0.105	+0.034	.001	.003	3	4
BREAST	Tie signaling pathway →	+0.717	+0.071	.001	<.001	3	3
BREAST	Blood coagulation, intrinsic pathway →	+0.206	+0.049	.002	.003	3	3
BREAST	Amelogenesis →	+0.210	+0.040	<.001	<.001	3	3
BREAST	Semi-lunar valve development →	+0.070	+0.023	.007	.009	3	3
BREAST	T cell selection →	+0.079	+0.042	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 455 associations by consensus.

Apoptotic cell clearance by TMCO5A expression — CNS

Explore this box plot interactively →