TMCO5A

Across TCGA pan-cancer cohorts, TMCO5A RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TMCO5A’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where TMCO5A RNA is repressed in tumor relative to normal tissue. In most cancer types TMCO5A is over-expressed in tumor, although a few such as STAD and LUSC show the opposite, repressed pattern.

STAD and LUSC are the cancer types where TMCO5A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMCO5A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	IV	−0.056	.001	9	view →
LUSC	All	II,III,IV	−0.028	.007	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TMCO5A–STAD

Open the STAD breakdown →