TMCO5A

Across TCGA cell cohorts, TMCO5A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TMCO5A-associated genes across cancer lineages are MAGEB4. Each is linked with TMCO5A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMCO5A-to-partner and partner-to-TMCO5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by TMCO5A-low versus TMCO5A-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO5A→partner) and Y-score (partner→TMCO5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MAGEB4 →	+0.006	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MAGEB4 by TMCO5A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →