Q-omics provides the consensus-scored TMBIM7P profile across patient tissues and cancer cell-line models. TMBIM7P expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, TMBIM7P is differentially expressed in 5, with the highest sampling consensus in LUSC. Additionally, TMBIM7P RNA expression shows 7,655 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight LIHC, LUSC, and TGCT as cancer lineages where TMBIM7P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TMBIM7P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TMBIM7P survival associations across molecular data types. TMBIM7P RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TMBIM7P RNA expression–survival associations across cancer types. High TMBIM7P expression shows unfavorable associations in LIHC, CHOL, ACC, PRAD, SKCM and BLCA. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for TMBIM7P RNA expression.
This table summarizes TMBIM7P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for TMBIM7P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TMBIM7P shows lower tumor expression in KIRP and higher tumor expression in LUSC, LUAD, KICH and PAAD. The LUSC box plot shows higher TMBIM7P RNA expression in tumor versus normal tissue (log2 FC = +0.134, t-test p < 0.001).
This table shows molecular features associated with TMBIM7P in patient tissues and cancer cell lines. In patient samples, TMBIM7P shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
