TMBIM1

Across TCGA patient cohorts, TMBIM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,584 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMBIM1-associated proteins across cancer lineages are EPS8L2, ANXA1, and ANXA2. Each is linked with TMBIM1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMBIM1-to-partner and partner-to-TMBIM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMBIM1 versus EPS8L2 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMBIM1→partner) and Y-score (partner→TMBIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EPS8L2 →	+0.616	+0.680	<.001	<.001	3	8
GBM	ANXA1 →	+0.861	+0.659	<.001	.001	3	7
GBM	ANXA2 →	+0.523	+0.488	<.001	<.001	3	7
HNSC	ITPRID2 →	+0.503	+0.996	<.001	<.001	3	6
GBM	SAAL1 →	-0.484	-0.583	<.001	<.001	3	6
LSCC	TDP1 →	-0.441	-0.591	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,584 associations by consensus.

TMBIM1 vs EPS8L2 — GBM

Explore this scatter interactively →