TMBIM1

Across TCGA patient cohorts, TMBIM1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,684 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMBIM1-associated genes across cancer lineages are FANCD2, METTL4, and SCML2. Each is linked with TMBIM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMBIM1-to-partner and partner-to-TMBIM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMBIM1 versus FANCD2 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMBIM1→partner) and Y-score (partner→TMBIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FANCD2 →	-0.759	-0.684	<.001	<.001	3	4
HNSC	METTL4 →	-0.401	-0.395	<.001	.008	3	3
HNSC	SCML2 →	-0.988	-0.579	<.001	<.001	3	3
HNSC	AADAT →	-0.864	-0.523	<.001	<.001	3	3
LUAD	CPSF6 →	-0.655	-0.315	.003	<.001	3	3
HNSC	MYB →	-0.876	-0.339	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,684 associations by consensus.

TMBIM1 vs FANCD2 — GBM

Explore this scatter interactively →