Across TCGA patient cohorts, TMA16 protein abundance is significantly associated with the RNA expression of many other genes, with 6,056 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMA16-associated genes across cancer lineages are SLC11A1, SNHG1, and GAS5. Each is linked with TMA16 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMA16-to-partner and partner-to-TMA16 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMA16→partner) and Y-score (partner→TMA16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC11A1 →	-0.970	-0.440	<.001	<.001	3	5
GBM	SNHG1 →	+0.571	+0.471	<.001	<.001	3	5
BRCA	GAS5 →	+0.617	+0.394	.001	<.001	3	5
BRCA	IL1R1 →	-0.789	-0.362	.002	<.001	3	4
GBM	TREM1 →	-1.445	-0.398	<.001	<.001	3	4
GBM	PELATON →	-0.615	-0.401	.001	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,056 associations by consensus.

Exploration

TMA16 survival (RNA) · tumor vs normal (RNA) · all TMA16 data types