TM9SF4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TM9SF4 mutation is significantly associated with the RNA expression of many other genes, with 1,380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TM9SF4-associated genes across cancer lineages are LINC02641, RN7SL237P, and OR8X1P. Each is linked with TM9SF4 in more than 2 cancer types. Because this analysis shows association rather than direction, both TM9SF4-to-partner and partner-to-TM9SF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02641 grouped by TM9SF4-low versus TM9SF4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM9SF4→partner) and Y-score (partner→TM9SF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC02641 →+0.170+2.381.001.00333
CESCRN7SL237P →+0.244+5.418<.001.00533
SKCMOR8X1P →+0.041+3.080<.001.00632
BLCARNA5SP199 →+0.200+3.043.002.00332
BLCARNA5SP516 →+0.129+4.040<.001.00732
SKCMLINC01817 →+0.041+3.469<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,380 associations by consensus.

LINC02641 by TM9SF4 expression — SKCM

Box plot of LINC02641 in TM9SF4-low vs TM9SF4-high samples in SKCM.

Explore this box plot interactively →

Exploration