TM7SF3

Across TCGA patient cohorts, TM7SF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,242 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TM7SF3-associated proteins across cancer lineages are SCFD1, CMAS, and SERPINA10. Each is linked with TM7SF3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TM7SF3-to-partner and partner-to-TM7SF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM7SF3 versus SCFD1 in LSCC, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TM7SF3→partner) and Y-score (partner→TM7SF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SCFD1 →	-0.311	-0.732	<.001	<.001	3	4
OV	CMAS →	+0.471	+0.597	.005	.007	3	4
GBM	SERPINA10 →	-0.535	-0.246	<.001	.005	3	4
HNSC	SRP54 →	-0.280	-0.794	<.001	<.001	3	4
BRCA	PKP2_S251 →	+0.952	+0.573	<.001	<.001	3	4
OV	PLEKHA5 →	+0.442	+0.664	.002	.006	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,242 associations by consensus.

TM7SF3 vs SCFD1 — LSCC

Explore this scatter interactively →