TM7SF3

Across TCGA patient cohorts, TM7SF3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,915 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TM7SF3-associated genes across cancer lineages are RNA5SP95, UHRF2P1, and FCGR2B. Each is linked with TM7SF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TM7SF3-to-partner and partner-to-TM7SF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM7SF3 versus RNA5SP95 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM7SF3→partner) and Y-score (partner→TM7SF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP95 →	+1.005	+0.335	.001	<.001	3	3
UCEC	UHRF2P1 →	+1.027	+0.424	.003	<.001	3	3
CCRCC	FCGR2B →	+0.714	+0.370	.008	.003	3	3
HNSC	LVRN →	-1.037	-0.799	<.001	<.001	3	3
UCEC	CNTN3 →	+1.487	+0.379	.001	.002	3	3
UCEC	KCNJ5 →	+1.200	+0.288	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,915 associations by consensus.

TM7SF3 vs RNA5SP95 — UCEC

Explore this scatter interactively →