TM7SF3

Across TCGA cell cohorts, TM7SF3 RNA expression is significantly associated with the RNA expression of many other genes, with 11,022 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TM7SF3-associated genes across cancer lineages are KLHL42, ETNK1, and C2CD5. Each is linked with TM7SF3 in more than 13 cancer types. Because this analysis shows association rather than direction, both TM7SF3-to-partner and partner-to-TM7SF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM7SF3 versus KLHL42 in LUNG_NSCLC_LUAD, with a Pearson correlation of 0.56.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM7SF3→partner) and Y-score (partner→TM7SF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KLHL42 →	+1.158	+0.886	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	ETNK1 →	+1.330	+1.310	<.001	<.001	3	12
LIVER	C2CD5 →	+1.115	+1.105	.001	.001	3	11
LUNG_NSCLC_LUAD	FGFR1OP2 →	+1.018	+0.919	<.001	<.001	3	11
STOMACH	IPO8 →	+1.314	+1.837	.002	<.001	3	11
LUNG_SCLC	MED21 →	+1.109	+1.594	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,022 associations by consensus.

TM7SF3 vs KLHL42 — LUNG_NSCLC_LUAD

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