TM7SF3

Across TCGA cell cohorts, TM7SF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TM7SF3-associated GO terms across cancer lineages are Glycerophospholipid biosynthetic process, Phospholipid biosynthetic process, and Copper ion export. Each is linked with TM7SF3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TM7SF3-to-partner and partner-to-TM7SF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerophospholipid biosynthetic process grouped by TM7SF3-low versus TM7SF3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TM7SF3→partner) and Y-score (partner→TM7SF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid biosynthetic process →	+0.036	+0.907	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.048	+1.361	.001	<.001	3	9
BLOOD_Leukemia	Copper ion export →	-0.229	-1.042	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.048	+1.489	<.001	<.001	3	8
PANCREAS	Cortical microtubule organization →	+0.096	+0.863	<.001	<.001	3	8
SKIN	Cytosolic transport →	+0.042	+0.667	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Glycerophospholipid biosynthetic process by TM7SF3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →