TM4SF5

Across TCGA patient cohorts, TM4SF5 protein abundance is significantly associated with the RNA expression of many other genes, with 628 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TM4SF5-associated genes across cancer lineages are IDH3B, SLC6A2, and BMF. Each is linked with TM4SF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM4SF5-to-partner and partner-to-TM4SF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM4SF5 versus IDH3B in COAD, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF5→partner) and Y-score (partner→TM4SF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IDH3B →	+1.345	+2.750	.006	.007	3	1
COAD	SLC6A2 →	-0.048	-2.331	.007	.006	3	1
COAD	BMF →	-0.923	-2.324	<.001	.006	3	1
COAD	SMURF2 →	-0.450	-2.331	.001	.006	3	1
COAD	USP45 →	-0.619	-2.619	.006	.001	3	1
COAD	OBSL1 →	-0.890	-2.619	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 628 associations by consensus.

TM4SF5 vs IDH3B — COAD

Explore this scatter interactively →