TM4SF4

Across TCGA cell cohorts, TM4SF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,676 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TM4SF4-associated GO terms across cancer lineages are Renal D-glucose absorption, Fatty acid metabolic process, and Vacuolar transport. Each is linked with TM4SF4 in more than 5 cancer types. Because this analysis shows association rather than direction, both TM4SF4-to-partner and partner-to-TM4SF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal D-glucose absorption grouped by TM4SF4-low versus TM4SF4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF4→partner) and Y-score (partner→TM4SF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Renal D-glucose absorption →	+1.366	+4.721	<.001	<.001	3	6
LIVER	Fatty acid metabolic process →	+0.061	+3.960	.002	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Vacuolar transport →	+0.059	+0.199	.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Cellular response to peptide hormone stimulus →	+0.044	+0.160	.001	.003	2	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of miRNA transcription →	+0.099	+0.159	<.001	<.001	3	5
OVARY	Response to rapamycin →	-0.125	-2.128	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,676 associations by consensus.

Renal D-glucose absorption by TM4SF4 expression — LIVER

Explore this box plot interactively →