TM4SF19-TCTEX1D2

Across TCGA pan-cancer cohorts, TM4SF19-TCTEX1D2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TM4SF19-TCTEX1D2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TM4SF19-TCTEX1D2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TM4SF19-TCTEX1D2 expression acts as an unfavorable survival marker, although some lineages such as PAAD and ESCA show a favorable association.

KIRC, ACC, and LIHC are the cancer types where TM4SF19-TCTEX1D2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.550	0.691	<.001	100	view →
ACC	DFS	Tertile	All	0.200	0.555	<.001	67	view →
LIHC	OS	Tertile	All	0.665	0.832	<.001	53	view →
PAAD	DFS	Median	All	0.541	0.243	<.001	36	view →
UVM	OS	Quartile	III,IV	0.306	0.772	.002	24	view →
PCPG	OS	Quartile	All	0.903	1.000	.005	24	view →
COAD	DFS	Median	All	0.726	0.827	.013	19	view →
ESCA	DFS	Quartile	All	0.867	0.333	.016	19	view →
KIRP	OS	Median	All	0.970	0.894	.003	16	view →
MESO	DFS	Quartile	IV	0.380	0.862	.005	12	view →
PRAD	DFS	Quartile	All	0.724	0.875	.012	12	view →
HNSC	DFS	Median	IV	0.575	0.702	.002	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TM4SF19-TCTEX1D2–KIRC (OS)

Open the KIRC breakdown →