TM4SF19-TCTEX1D2

Across TCGA pan-cancer cohorts, TM4SF19-TCTEX1D2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TM4SF19-TCTEX1D2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TM4SF19-TCTEX1D2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TM4SF19-TCTEX1D2 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, LUSC, and COAD are the cancer types where TM4SF19-TCTEX1D2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TM4SF19-TCTEX1D2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.618	<.001	12	view →
LUSC	Male	All	+0.314	<.001	7	view →
COAD	All	II,III,IV	+0.082	<.001	6	view →
KIRC	Male	All	+0.038	<.001	6	view →
BLCA	All	IV	+0.140	.016	3	view →
KICH	Female	III,IV	−0.073	<.001	3	view →
CHOL	Male	All	+0.283	<.001	2	view →
READ	All	All	+0.097	.040	2	view →
PRAD	All	All	+0.031	.047	2	view →
LIHC	All	All	+0.029	.010	2	view →
STAD	All	III,IV	+0.141	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TM4SF19-TCTEX1D2–HNSC

Open the HNSC breakdown →