TM4SF19-AS1

Across TCGA pan-cancer cohorts, TM4SF19-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TM4SF19-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TM4SF19-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TM4SF19-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

KIRC, COAD, and LIHC are the cancer types where TM4SF19-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.748	0.861	<.001	123	view →
COAD	OS	Median	All	0.468	0.707	.003	53	view →
LIHC	DFS	Quartile	All	0.418	0.657	<.001	48	view →
LUAD	DFS	Median	All	0.256	0.445	.005	36	view →
KICH	OS	Tertile	All	0.725	1.000	.007	30	view →
THCA	DFS	Quartile	II,III,IV	0.872	0.934	.013	27	view →
UVM	DFS	Median	All	0.537	0.934	.002	22	view →
MESO	DFS	Tertile	IV	0.142	0.552	.006	21	view →
READ	DFS	Median	All	0.381	0.768	.001	17	view →
UCS	OS	Quartile	II,III,IV	0.735	0.267	.013	16	view →
BLCA	DFS	Tertile	IV	0.236	0.608	.006	12	view →
BRCA	OS	Tertile	IV	0.677	0.191	.016	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TM4SF19-AS1–KIRC (DFS)

Open the KIRC breakdown →