TLX1NB

Across TCGA patient cohorts, TLX1NB RNA expression is significantly associated with the go_rna of many other GO terms, with 6,951 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible TLX1NB-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Microtubule organizing center organization, and Regulation of DNA repair. Each is linked with TLX1NB in more than 12 cancer types. Because this analysis shows association rather than direction, both TLX1NB-to-partner and partner-to-TLX1NB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by TLX1NB-low versus TLX1NB-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLX1NB→partner) and Y-score (partner→TLX1NB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of double-strand break repair via homologous recombination →	+0.051	+0.307	<.001	.001	3	13
STAD	Microtubule organizing center organization →	+0.071	+0.145	<.001	<.001	3	13
ESCA	Regulation of DNA repair →	+0.049	+0.280	.002	.003	3	13
STAD	Transcription by RNA polymerase I →	+0.051	+0.085	<.001	<.001	3	13
STAD	Obsolete histone deacetylation →	+0.063	+0.150	<.001	<.001	3	12
STAD	RNA capping →	+0.047	+0.104	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,951 associations by consensus.

Regulation of double-strand break repair via homologous recombination by TLX1NB expression — ESCA

Explore this box plot interactively →