TLX1NB

Across TCGA patient cohorts, TLX1NB mutation is significantly associated with the RNA expression of many other genes, with 1,099 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TLX1NB-associated genes across cancer lineages are RN7SL462P, TRIM43B, and OR5E1P. Each is linked with TLX1NB in more than 1 cancer types. Because this analysis shows association rather than direction, both TLX1NB-to-partner and partner-to-TLX1NB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL462P grouped by TLX1NB-low versus TLX1NB-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLX1NB→partner) and Y-score (partner→TLX1NB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL462P →	+0.153	+7.731	<.001	.009	3	1
COAD	TRIM43B →	+0.061	+6.721	<.001	<.001	3	1
SKCM	OR5E1P →	+0.055	+5.292	<.001	.006	3	1
SKCM	CST9 →	+0.063	+5.292	<.001	.006	3	1
SKCM	RNA5SP319 →	+0.355	+5.097	<.001	.008	3	1
SKCM	RNA5SP149 →	+0.443	+5.292	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,099 associations by consensus.

RN7SL462P by TLX1NB expression — BRCA

Explore this box plot interactively →