TLR10

Across TCGA patient cohorts, TLR10 protein abundance is significantly associated with the RNA expression of many other genes, with 2,796 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TLR10-associated genes across cancer lineages are SEC14L3, UPB1, and CYTH4. Each is linked with TLR10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLR10-to-partner and partner-to-TLR10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLR10 versus SEC14L3 in CCRCC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLR10→partner) and Y-score (partner→TLR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEC14L3 →	-0.054	-0.981	.006	.005	3	1
CCRCC	UPB1 →	+0.679	+1.259	.006	<.001	3	1
CCRCC	CYTH4 →	-0.522	-1.110	<.001	<.001	3	1
CCRCC	SH3BP1 →	-0.255	-0.879	<.001	.001	3	1
CCRCC	GCAT →	+0.570	+1.085	.003	.001	3	1
CCRCC	EIF3L →	+0.331	+1.051	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,796 associations by consensus.

TLR10 vs SEC14L3 — CCRCC

Explore this scatter interactively →