TLR10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TLR10 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,242 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TLR10-associated proteins across cancer lineages are APOBR_S175, MT-ND1, and MT2A_S58. Each is linked with TLR10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLR10-to-partner and partner-to-TLR10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLR10 versus APOBR_S175 in CCRCC, with a Pearson correlation of -0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLR10→partner) and Y-score (partner→TLR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCAPOBR_S175 →-0.555-1.193<.001<.00131
CCRCCMT-ND1 →+0.730+1.597<.001<.00131
CCRCCMT2A_S58 →+1.398+1.381<.001<.00131
CCRCCMTHFS →+0.460+1.118<.001<.00131
CCRCCMTMR12_S564 →+0.323+0.913<.001.00131
CCRCCMTPN_T31 →-0.247-1.142.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,242 associations by consensus.

TLR10 vs APOBR_S175 — CCRCC

Per-sample scatter of TLR10 vs APOBR_S175 in CCRCC (Pearson r = -0.41).

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Exploration