TLR10

Across TCGA cell cohorts, TLR10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,259 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TLR10-associated GO terms across cancer lineages are Detection of bacterial lipopeptide, Regulation of mRNA splicing, via spliceosome, and Response to UV. Each is linked with TLR10 in more than 10 cancer types. Because this analysis shows association rather than direction, both TLR10-to-partner and partner-to-TLR10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detection of bacterial lipopeptide grouped by TLR10-low versus TLR10-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLR10→partner) and Y-score (partner→TLR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Detection of bacterial lipopeptide →	+1.212	+3.313	<.001	<.001	3	11
PANCREAS	Regulation of mRNA splicing, via spliceosome →	+0.070	+0.110	<.001	.001	3	8
CNS	Response to UV →	+0.033	+0.047	<.001	.001	3	8
OVARY	Negative regulation of myoblast fusion →	+0.122	+0.040	<.001	<.001	3	7
PANCREAS	Maintenance of location →	+0.049	+0.057	.002	.005	3	7
PANCREAS	Protein localization to lysosome →	+0.060	+0.082	.002	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,259 associations by consensus.

Detection of bacterial lipopeptide by TLR10 expression — BLOOD_Lymphoma

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