TLNRD1

Across TCGA patient cohorts, TLNRD1 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TLNRD1-associated genes across cancer lineages are MIR7843, LYZL1, and RNA5SP325. Each is linked with TLNRD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLNRD1-to-partner and partner-to-TLNRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7843 grouped by TLNRD1-low versus TLNRD1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLNRD1→partner) and Y-score (partner→TLNRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR7843 →	+0.538	+5.279	<.001	.006	3	2
CESC	LYZL1 →	+0.090	+5.418	<.001	.005	3	1
CESC	RNA5SP325 →	+0.344	+6.837	<.001	<.001	3	1
UCEC	SLCO1B1 →	+0.663	+3.613	<.001	.008	3	1
UCEC	JTBP1 →	+0.488	+3.822	.008	.005	3	1
UCEC	RN7SL98P →	+0.237	+3.845	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MIR7843 by TLNRD1 expression — LUAD

Explore this box plot interactively →