TLNRD1

Across TCGA pan-cancer cohorts, TLNRD1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TLNRD1 data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TLNRD1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TLNRD1 expression acts as an unfavorable survival marker, although some lineages such as SCLC and UCEC show a favorable association.

LUAD, KIRP, and ACC are the cancer types where TLNRD1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.531	0.749	<.001	88	view →
KIRP	DFS	Tertile	II,III,IV	0.501	0.844	.001	87	view →
ACC	DFS	Median	All	0.243	0.669	<.001	86	view →
SCLC	OS	Tertile	All	0.856	0.514	<.001	76	view →
UCEC	DFS	Quartile	II,III,IV	0.901	0.703	<.001	74	view →
HNSC	OS	Quartile	All	0.675	0.814	.001	49	view →
UVM	OS	Median	III,IV	0.240	0.836	.001	42	view →
KIRC	DFS	Median	All	0.738	0.511	.002	42	view →
LGG	DFS	Tertile	All	0.650	0.850	<.001	41	view →
LUSC	DFS	Quartile	II,III,IV	0.572	0.748	.010	33	view →
DLBC	DFS	Median	All	0.629	1.000	.017	23	view →
LIHC	OS	Tertile	III,IV	0.317	0.701	.002	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TLNRD1–LUAD (DFS)

Open the LUAD breakdown →