TLNRD1

Across TCGA cell cohorts, TLNRD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,566 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TLNRD1-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Negative regulation of mRNA splicing, via spliceosome. Each is linked with TLNRD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TLNRD1-to-partner and partner-to-TLNRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA splicing grouped by TLNRD1-low versus TLNRD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLNRD1→partner) and Y-score (partner→TLNRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of RNA splicing →	+0.084	+1.548	.002	<.001	3	12
SOFT_TISSUE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.132	+0.796	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA splicing, via spliceosome →	+0.108	+0.869	<.001	<.001	3	12
BREAST	Regulation of protein localization to nucleus →	+0.086	+0.963	<.001	.001	3	12
URINARY_TRACT	Negative regulation of DNA-templated transcription initiation →	+0.131	+0.819	<.001	<.001	3	12
URINARY_TRACT	Negative regulation of transcription initiation by RNA polymerase II →	+0.131	+0.819	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,566 associations by consensus.

Negative regulation of RNA splicing by TLNRD1 expression — BONE

Explore this box plot interactively →