TLN2

Across TCGA patient cohorts, TLN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,326 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TLN2-associated proteins across cancer lineages are SEPTIN11, DPYSL3, and FBLN1. Each is linked with TLN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TLN2-to-partner and partner-to-TLN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLN2 versus SEPTIN11 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLN2→partner) and Y-score (partner→TLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEPTIN11 →	+0.331	+0.634	<.001	<.001	3	6
BRCA	DPYSL3 →	+0.638	+0.743	<.001	<.001	3	6
HNSC	FBLN1 →	+0.789	+0.799	<.001	<.001	3	6
OV	RAB23 →	+0.417	+0.713	.001	.002	3	6
BRCA	NUMBL →	+0.331	+0.609	<.001	<.001	3	5
HNSC	OMD →	+1.405	+0.609	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,326 associations by consensus.

TLN2 vs SEPTIN11 — HNSC

Explore this scatter interactively →