TLN2

Across TCGA patient cohorts, TLN2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,633 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TLN2-associated genes across cancer lineages are MYL3, KLHDC1, and TIMP3. Each is linked with TLN2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TLN2-to-partner and partner-to-TLN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLN2 versus MYL3 in HNSC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLN2→partner) and Y-score (partner→TLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYL3 →	+1.404	+0.565	<.001	<.001	3	10
BRCA	KLHDC1 →	+0.699	+0.475	<.001	<.001	3	10
BRCA	TIMP3 →	+1.709	+0.640	<.001	<.001	3	9
OV	SYDE1 →	+0.714	+0.321	<.001	<.001	3	9
BRCA	RECK →	+1.321	+0.784	<.001	<.001	3	9
UCEC	SSPN →	+0.856	+0.442	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,633 associations by consensus.

TLN2 vs MYL3 — HNSC

Explore this scatter interactively →