TLN2

Across TCGA cell cohorts, TLN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,713 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TLN2-associated GO terms across cancer lineages are Schwann cell development, Regulation of nucleotide-excision repair, and Nucleoside triphosphate biosynthetic process. Each is linked with TLN2 in more than 10 cancer types. Because this analysis shows association rather than direction, both TLN2-to-partner and partner-to-TLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Schwann cell development grouped by TLN2-low versus TLN2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLN2→partner) and Y-score (partner→TLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Schwann cell development →	+0.091	+1.603	<.001	<.001	3	11
OESOPHAGUS	Regulation of nucleotide-excision repair →	+0.121	+1.643	.002	<.001	3	10
BLOOD_Lymphoma	Nucleoside triphosphate biosynthetic process →	+0.073	+0.913	<.001	<.001	3	10
URINARY_TRACT	Regulation of protein-containing complex disassembly →	+0.041	+1.143	<.001	<.001	3	10
BONE	Schwann cell differentiation →	+0.104	+1.521	<.001	<.001	3	10
BLOOD_Lymphoma	Purine nucleoside triphosphate biosynthetic process →	+0.077	+0.981	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,713 associations by consensus.

Schwann cell development by TLN2 expression — BONE

Explore this box plot interactively →