TLE7

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, TLE7 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TLE7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where TLE7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TLE7 is over-expressed in tumor.

KIRP and LUAD are the cancer types where TLE7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TLE7 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRPAllAll+0.029.0243view →
LUADAllAll+0.041.0491view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TLE7–KIRP

Tumor-vs-normal expression box plot for TLE7 RNA in KIRP.

Open the KIRP breakdown →

Exploration