TLE6

Across TCGA cell cohorts, TLE6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,532 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TLE6-associated GO terms across cancer lineages are Protein storage, Endoplasmic reticulum localization, and Wound healing. Each is linked with TLE6 in more than 19 cancer types. Because this analysis shows association rather than direction, both TLE6-to-partner and partner-to-TLE6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein storage grouped by TLE6-low versus TLE6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLE6→partner) and Y-score (partner→TLE6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein storage →	+1.528	+2.056	<.001	<.001	3	20
SKIN	Endoplasmic reticulum localization →	-0.137	-1.112	<.001	<.001	3	11
BONE	Wound healing →	-0.097	-0.985	<.001	.002	3	9
BONE	Regulation of fibrinolysis →	-0.435	-1.515	.001	.001	3	9
BONE	Regulation of response to wounding →	-0.146	-1.360	.003	.002	2	9
STOMACH	Endodermal cell differentiation →	-0.137	-1.619	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,532 associations by consensus.

Protein storage by TLE6 expression — BONE

Explore this box plot interactively →