TLCD3B

Across TCGA patient cohorts, TLCD3B mutation is significantly associated with the RNA expression of many other genes, with 1,828 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TLCD3B-associated genes across cancer lineages are RNA5SP181, SAP18P1, and RNA5SP35. Each is linked with TLCD3B in more than 2 cancer types. Because this analysis shows association rather than direction, both TLCD3B-to-partner and partner-to-TLCD3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP181 grouped by TLCD3B-low versus TLCD3B-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3B→partner) and Y-score (partner→TLCD3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA5SP181 →	+0.509	+5.274	<.001	.006	3	3
COAD	SAP18P1 →	+0.878	+5.357	<.001	.006	3	3
CESC	RNA5SP35 →	+0.315	+5.201	<.001	.007	3	2
SKCM	TIPINP1 →	+0.052	+2.978	<.001	.007	3	2
UCEC	GAK →	+0.446	+3.483	.001	.002	3	2
UCEC	LSM10 →	+0.578	+3.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,828 associations by consensus.

RNA5SP181 by TLCD3B expression — STAD

Explore this box plot interactively →