TLCD3B

Across TCGA pan-cancer cohorts, TLCD3B RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated TLCD3B data layer compared with 5 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher TLCD3B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TLCD3B expression acts as an unfavorable survival marker, although some lineages such as LGG and CESC show a favorable association.

KIRP, KIRC, and LGG are the cancer types where TLCD3B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.789	0.914	<.001	100	view →
KIRC	DFS	Median	All	0.503	0.718	<.001	98	view →
LGG	OS	Median	All	0.542	0.342	<.001	54	view →
CESC	OS	Tertile	All	0.901	0.763	.004	50	view →
BRCA	OS	Quartile	III,IV	0.940	0.782	<.001	45	view →
LIHC	DFS	Median	All	0.458	0.625	<.001	41	view →
ACC	DFS	Quartile	All	0.242	0.762	<.001	36	view →
UVM	OS	Tertile	All	0.537	1.000	.004	34	view →
UCS	OS	Quartile	II,III,IV	0.209	0.767	.007	24	view →
MESO	OS	Median	All	0.293	0.473	.005	24	view →
READ	DFS	Median	All	0.776	0.260	.006	22	view →
COAD	DFS	Tertile	All	0.727	0.841	.003	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

TLCD3B–KIRP (DFS)

Open the KIRP breakdown →