TLCD3B

Across TCGA cell cohorts, TLCD3B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,944 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TLCD3B-associated GO terms across cancer lineages are Positive regulation of intracellular estrogen receptor signaling pathway, Mitotic cytokinesis, and Regulation of myoblast fusion. Each is linked with TLCD3B in more than 12 cancer types. Because this analysis shows association rather than direction, both TLCD3B-to-partner and partner-to-TLCD3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular estrogen receptor signaling pathway grouped by TLCD3B-low versus TLCD3B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3B→partner) and Y-score (partner→TLCD3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.224	+1.779	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Mitotic cytokinesis →	+0.054	+0.616	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.086	+0.489	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.093	+0.404	<.001	.001	3	12
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.162	+1.308	.001	.003	2	12
LUNG_SCLC	Cytoskeleton-dependent cytokinesis →	+0.055	+1.378	<.001	.008	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,944 associations by consensus.

Positive regulation of intracellular estrogen receptor signaling pathway by TLCD3B expression — BONE

Explore this box plot interactively →