TLCD3A

Across TCGA patient cohorts, TLCD3A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,435 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TLCD3A-associated proteins across cancer lineages are SMC2, MCM2, and MCM4. Each is linked with TLCD3A in more than 5 cancer types. Because this analysis shows association rather than direction, both TLCD3A-to-partner and partner-to-TLCD3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLCD3A versus SMC2 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3A→partner) and Y-score (partner→TLCD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC2 →	+0.515	+0.383	<.001	<.001	3	6
GBM	MCM2 →	+0.547	+0.351	<.001	.001	3	6
GBM	MCM4 →	+0.639	+0.483	<.001	<.001	3	6
GBM	MCM7 →	+0.640	+0.473	<.001	.001	3	6
BRCA	FXR2 →	+0.364	+1.029	<.001	<.001	3	6
LSCC	MYBBP1A →	+0.366	+0.610	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,435 associations by consensus.

TLCD3A vs SMC2 — GBM

Explore this scatter interactively →