TKFC

Across TCGA patient cohorts, TKFC RNA expression is significantly associated with the protein abundance of many other proteins, with 13,593 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TKFC-associated proteins across cancer lineages are DDB1, ZKSCAN1, and TOM1L1. Each is linked with TKFC in more than 6 cancer types. Because this analysis shows association rather than direction, both TKFC-to-partner and partner-to-TKFC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TKFC versus DDB1 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TKFC→partner) and Y-score (partner→TKFC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDB1 →	+0.224	+0.585	<.001	<.001	3	7
UCEC	ZKSCAN1 →	+0.349	+0.730	<.001	.001	3	5
BRCA	TOM1L1 →	+0.529	+0.577	<.001	<.001	3	5
BRCA	CBR4 →	+0.554	+0.560	<.001	.003	3	5
BRCA	CMBL →	+0.654	+0.473	<.001	<.001	3	5
GBM	CPSF7 →	+0.337	+0.379	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,593 associations by consensus.

TKFC vs DDB1 — LSCC

Explore this scatter interactively →