TKFC

Across TCGA patient cohorts, TKFC protein abundance is significantly associated with the protein abundance of many other proteins, with 18,045 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TKFC-associated proteins across cancer lineages are CMBL, IVD, and PTGR2. Each is linked with TKFC in more than 7 cancer types. Because this analysis shows association rather than direction, both TKFC-to-partner and partner-to-TKFC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TKFC versus CMBL in BRCA, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TKFC→partner) and Y-score (partner→TKFC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CMBL →	+0.889	+0.425	<.001	<.001	3	8
OV	IVD →	+0.774	+0.524	<.001	<.001	3	8
LUAD	PTGR2 →	+0.506	+0.288	<.001	<.001	2	8
UCEC	MYO9B →	-0.321	-0.331	<.001	<.001	3	7
BRCA	FCSK →	+0.368	+0.533	<.001	<.001	3	7
CCRCC	GFPT2 →	-0.948	-0.354	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,045 associations by consensus.

TKFC vs CMBL — BRCA

Explore this scatter interactively →