TJAP1

Across TCGA patient cohorts, TJAP1 mutation is significantly associated with the RNA expression of many other genes, with 969 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TJAP1-associated genes across cancer lineages are GAGE2E, CCL3, and TMEM11. Each is linked with TJAP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TJAP1-to-partner and partner-to-TJAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE2E grouped by TJAP1-low versus TJAP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TJAP1→partner) and Y-score (partner→TJAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GAGE2E →	+0.142	+8.153	<.001	<.001	3	3
UCEC	CCL3 →	+0.766	+2.102	<.001	.001	3	2
UCEC	TMEM11 →	+0.316	+3.202	.003	.009	3	2
UCEC	ALKBH5 →	+0.446	+3.160	<.001	<.001	3	2
UCEC	FZR1 →	+0.377	+2.470	.001	<.001	3	2
UCEC	TPI1 →	+0.474	+4.040	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 969 associations by consensus.

GAGE2E by TJAP1 expression — COAD

Explore this box plot interactively →