TIPRL

Across TCGA patient cohorts, TIPRL mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIPRL-associated genes across cancer lineages are Adipocytes, GMP, and Neutrophils. Each is linked with TIPRL in more than 1 cancer types. Because this analysis shows association rather than direction, both TIPRL-to-partner and partner-to-TIPRL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by TIPRL-low versus TIPRL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIPRL→partner) and Y-score (partner→TIPRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.040	+2.851	.001	.044	3	1
UCEC	GMP →	+0.141	+3.027	.001	.042	3	1
UCEC	Neutrophils →	+0.058	+3.166	<.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by TIPRL expression — UCEC

Explore this box plot interactively →