TIPRL

Across TCGA cell cohorts, TIPRL protein abundance is significantly associated with the RNA expression of many other genes, with 3,946 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TIPRL-associated genes across cancer lineages are EEA1, KLHL4, and FOXF1. Each is linked with TIPRL in more than 1 cancer types. Because this analysis shows association rather than direction, both TIPRL-to-partner and partner-to-TIPRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIPRL versus EEA1 in CNS, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIPRL→partner) and Y-score (partner→TIPRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	EEA1 →	-0.413	-1.389	.008	<.001	3	1
CNS	KLHL4 →	+3.050	+1.292	.001	.001	3	1
CNS	FOXF1 →	+2.062	+1.350	.002	<.001	3	1
CNS	ELOB →	+0.885	+1.367	.003	.004	3	1
CNS	BET1 →	+0.646	+1.400	.004	.002	3	1
CNS	FSD1L →	-1.335	-1.545	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,946 associations by consensus.

TIPRL vs EEA1 — CNS

Explore this scatter interactively →