Across TCGA patient cohorts, TINCR mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TINCR-associated genes across cancer lineages are MIR188, RPL23AP90, and MIR6753. Each is linked with TINCR in more than 1 cancer types. Because this analysis shows association rather than direction, both TINCR-to-partner and partner-to-TINCR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TINCR→partner) and Y-score (partner→TINCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR188 →	+0.292	+4.582	<.001	<.001	3	2
UCEC	RPL23AP90 →	+0.527	+3.226	<.001	.002	3	1
UCEC	MIR6753 →	+0.627	+3.459	.004	.006	3	1
UCEC	RNVU1-28 →	+1.019	+2.635	<.001	.008	3	1
UCEC	RN7SL478P →	+0.360	+2.676	<.001	.007	3	1
UCEC	IL21 →	+0.221	+3.026	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

Exploration

TINCR survival (RNA) · tumor vs normal (RNA) · all TINCR data types