Across TCGA pan-cancer cohorts, TINCR RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TINCR data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TINCR RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TINCR expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

KIRC, KICH, and ACC are the cancer types where TINCR RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.507	0.737	<.001	134	view →
KICH	DFS	Median	II,III,IV	0.513	1.000	<.001	89	view →
ACC	DFS	Median	All	0.433	0.727	.001	83	view →
KIRP	DFS	Quartile	All	0.472	0.726	<.001	53	view →
SKCM	OS	Median	All	0.243	0.381	<.001	47	view →
UCEC	DFS	Median	All	0.542	0.734	<.001	38	view →
HNSC	OS	Median	III,IV	0.799	0.683	.007	35	view →
CESC	DFS	Tertile	All	0.890	0.741	.002	32	view →
PCPG	DFS	Quartile	All	0.941	0.755	.015	20	view →
LUSC	DFS	Quartile	All	0.820	0.607	.014	17	view →
UVM	DFS	Quartile	III,IV	0.182	1.000	.006	16	view →
LUAD	DFS	Median	IV	0.666	0.978	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration

Same gene, other analysis: TINCR tumor-vs-normal RNA expression · all TINCR data types