TINAG

Across TCGA patient cohorts, TINAG protein abundance is significantly associated with the RNA expression of many other genes, with 921 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TINAG-associated genes across cancer lineages are LHFPL3, LHFPL3-AS2, and TINAG-AS1. Each is linked with TINAG in more than 1 cancer types. Because this analysis shows association rather than direction, both TINAG-to-partner and partner-to-TINAG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TINAG versus LHFPL3 in PDAC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TINAG→partner) and Y-score (partner→TINAG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LHFPL3 →	+1.165	+0.742	<.001	.007	3	2
PDAC	LHFPL3-AS2 →	+1.813	+0.906	.001	.002	3	2
CCRCC	TINAG-AS1 →	+1.009	+0.648	.001	<.001	3	2
PDAC	RPS29P32 →	+0.928	+0.917	<.001	<.001	3	2
CCRCC	MIOX →	+1.636	+0.521	<.001	.006	3	1
CCRCC	SERPINA4 →	-0.465	-0.442	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 921 associations by consensus.

TINAG vs LHFPL3 — PDAC

Explore this scatter interactively →