TIMMDC1

Across TCGA cell cohorts, TIMMDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,080 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TIMMDC1-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Positive regulation of viral genome replication, and Endosomal lumen acidification. Each is linked with TIMMDC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TIMMDC1-to-partner and partner-to-TIMMDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by TIMMDC1-low versus TIMMDC1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMMDC1→partner) and Y-score (partner→TIMMDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Establishment of protein localization to organelle →	+0.047	+0.930	<.001	.002	3	11
OVARY	Positive regulation of viral genome replication →	+0.112	+0.631	<.001	.001	3	10
CNS	Endosomal lumen acidification →	+0.083	+0.322	.001	.006	3	9
BLOOD_Lymphoma	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.046	+0.586	.001	<.001	3	9
BLOOD_Leukemia	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.061	+0.413	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Telomerase RNA localization to Cajal body →	+0.086	+0.954	.006	.008	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,080 associations by consensus.

Establishment of protein localization to organelle by TIMMDC1 expression — BLOOD_Myeloma

Explore this box plot interactively →