TIMM9

Across TCGA patient cohorts, TIMM9 mutation is significantly associated with the RNA expression of many other genes, with 1,411 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIMM9-associated genes across cancer lineages are MIR4701, MIR5188, and MIR4445. Each is linked with TIMM9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIMM9-to-partner and partner-to-TIMM9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4701 grouped by TIMM9-low versus TIMM9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM9→partner) and Y-score (partner→TIMM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4701 →	+0.781	+2.293	.004	.006	3	1
UCEC	MIR5188 →	+0.800	+2.328	<.001	.004	3	1
UCEC	MIR4445 →	+0.248	+5.019	<.001	.001	3	1
UCEC	ATP6V1E1P2 →	+0.142	+2.398	.007	.007	3	1
UCEC	ASB16-AS1 →	+0.690	+3.606	<.001	.001	3	1
UCEC	ZSCAN5DP →	+0.516	+3.627	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,411 associations by consensus.

MIR4701 by TIMM9 expression — UCEC

Explore this box plot interactively →